The (Greek) Key to Structures of Neural Adhesion Molecules

نویسندگان

  • Daniel E Vaughn
  • Pamela J Bjorkman
چکیده

regions of many neural CAMs. Cadherins are also imporCells need toadhere specifically to cellular and extraceltant neural CAMs, forming homophilic adhesion interlular components of their environment to carry out difaces in the presence of calcium (Geiger and Ayalon, verse physiological functions. Examples of such func1992). Two recent structures of cadherin domains protions within the nervous system include neurite vide a clue about how the adhesive interface is formed. extension, synapse formation, and the myelination of The classification of Ig-like domains has evolved since axons. The ability to recognize multiple environmental

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عنوان ژورنال:
  • Neuron

دوره 16  شماره 

صفحات  -

تاریخ انتشار 1996